Precision Oncology

Oncologica’s linking of specific cancer genetic mutations to molecular targeted therapies is driving a new era of personalised medicine

Oncologica’s precision medicine exploits NGS molecular profiling to enable a patient’s tumour to be matched directly with the most appropriate molecular targeted therapy.

Chemotherapy or radiation treatments target cellular mechanisms common to both healthy and cancerous cells, whilst therapies based on somatic genomic mutations can direct treatment specifically to tumours based on their genomic molecular blueprint.

Management of cancer patients is changing rapidly as comprehensive genomic assessment of cancer reveals novel therapeutic targets and opportunities for new clinical treatments. Several cancer therapies already exist that target specific alterations in cancer driver genes such as Trastuzumab which targets breast and gastric cancers overexpressing the HER2/neu protein, tyrosine kinase inhibitors (TKIs) targeting aberrant EGFR receptor in lung, colorectal and pancreatic cancers, and vemurafenib targeting BRAF in melanoma and several other cancer types.

Using state of the art semiconductor sequencing and convergent informatics pipelines, UK based genetic contract research organisation Oncologica has introduced the most comprehensive single integrated test that analyses all major cancer driver genes for thousands of actionable mutations.

Oncologica’s genetic testing centre links these mutations to hundreds of targeted therapies using our informatics pipeline which is linked to the world’s largest curated compendium of cancer genomic information, to support the matching of driver genetic mutations with relevant clinical therapeutic options.

Select

Discuss your bioinformatic research requirements and select the gene panel with our genetic reasearch team that suits your project needs.

Prepare

We prepare a fully optimised cancer panel specific to your requirements.

Validate

We validate the performance of the panel in our our laboratory.

Genetic Contract Research

Our precision oncology genetic testing services provide complex and accurate molecular testing solutions for oncological, cardiovascular, genetic, ophthalmic and orthopedic disorders.Our expert genetic research services significantly shorten development timescales.

Undertake

As your genetic research testing partner, Oncologica undertake advanced bioinformatics research and contract pharmacogenetic testing for clinical trials. 

Experience

Access superior genetic sequencing skills, methodologies and technologies for genetic drug development assays

Uncover

Uncover new discoveries in cancer biology and drive change in drug development.